Fmoc-L-Glutamic Acid Γ-Methyl Ester - Names and Identifiers
Fmoc-L-Glutamic Acid Γ-Methyl Ester - Physico-chemical Properties
Molecular Formula | C21H21NO6
|
Molar Mass | 383.39 |
Density | 1.296±0.06 g/cm3(Predicted) |
Boling Point | 625.3±55.0 °C(Predicted) |
Appearance | Powder |
Color | White |
pKa | 3.70±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Physical and Chemical Properties | Storage Conditions: Store at 0-5 ℃ |
Fmoc-L-Glutamic Acid Γ-Methyl Ester - Introduction
Fmoc-L-Glutamic acid gamma-methyl ester is an organic compound with the following properties:
1. Appearance: Fmoc-L-Glutamic acid gamma-methyl ester is a white crystalline solid.
2. Stability: This compound is relatively stable at room temperature.
3. Solubility: Fmoc-L-Glutamic acid gamma-methyl ester is soluble in some organic solvents (such as dimethyl sulfoxide, dichloromethane, etc.).
The main purpose of Fmoc-L-Glutamic acid gamma-methyl ester is to be used as a protecting group in the synthesis of peptides to control the reactivity of amino acids. It can be synthesized:
1. First, dissolve L-glutamic acid in sodium carbonate solution, and then add Fmoc-Cl. After the reaction proceeds, Fmoc-L-glutamic acid can be obtained.
2. Next, methanol and benzylidene chloride were added to the sodium carbonate solution. After the reaction, the Fmoc-L-Glutamic acid gamma-methyl ester can be obtained.
When using the Fmoc-L-Glutamic acid gamma-methyl ester, you need to pay attention to safety precautions:
1. This compound may be irritating to the eyes, skin and respiratory system, so protective measures should be taken when exposed, such as wearing protective glasses, gloves and masks.
2. Avoid inhaling dust or vapor from the solution, as respiratory irritation and discomfort may occur.
3. In use and storage, should be away from the fire and combustible.
4. Waste disposal should comply with local regulations to ensure safety.
Last Update:2024-04-09 21:21:28